The Dutch School painters can be dated as Early Netherlandish (1400–1500), Dutch Renaissance (1500–1584), and, later, Dutch Golden Age painting in the United Provinces. The detailed realism of Early Netherlandish painting, led by Robert Campin and Jan van Eyck in the 1420s and 1430s, is today generally considered to be the beginning of the early Northern Renaissance in painting. This style was greatly respected in Italy, but there was little reciprocal influence on the North until nearly the end of the 15th century. Despite frequent cultural and artistic exchange, the Antwerp Mannerists (1500–1530) were unrelated to Italian Mannerism. Among notable northern painters were highly individualistic artists such as Hieronymus Bosch and Pieter Bruegel the Elder who developed styles that were imitated by many subsequent generations. In the 16th century northern painters increasingly traveled to Italy, so the art of Michelangelo and Raphael and the late Renaissance Mannerism had a great impact on their work. Hieronymus Bosch and Geertgen tot Sint Jans are well-known examples of fifteenth- and sixteenth-century Dutch painters. In the northern Netherlands, the Reformation brought religious painting almost completely to an end. Portrait painting was slow to spread from the elite to new riches. By the end of the 16th century, artists such as Karel van Mander and Hendrik Goltzius collected in Haarlem in a brief but intense phase of Northern Mannerism that also spread to Flanders. Between 1605 and 1635 over 100,000 paintings were produced in Haarlem. Rembrandt van Rijn, Frans Hals, Johannes Vermeer, Jacob van Ruisdael, and Jan Steen are just a few names form the seventeenth century.
The Dutch Golden Age was a period from 1581 to 1672, when the Netherlands experienced the "Dutch Miracle", transcended to the foremost maritime and economic power. In 1568, the Seven Provinces started a rebellion against Philip II of Spain, leading to the Eighty Years' War with Spain and the Thirty Years' War between other European superpowers. Protestants moved from the southern to the northern Netherlands, many settled in Amsterdam, transforming a port town into one of the most important commercial centers in the world by 1630. In addition to the migration of Protestants, there were also influxes of refugees who had previously fled from religious persecution, particularly Sephardi Jews from Portugal and Spain, and Protestants from France. Catholics moved in the other direction - to the southern provinces, modern Belgium. North quickly gained the highest literacy rates in Europe, an abundance of capital, the largest merchant fleet in Europe. The Dutch dominated trade in the Baltic Sea, between China and Japan, and with the English colonies in North America. The Dutch East India Company (VOC) was the first multinational corporation, financed by shares that established the first modern stock exchange. The Bank of Amsterdam, the first central bank, was established in 1609. The Dutch Golden Age is the art period dominanted by Rembrandt, Vermeer, Jacob van Ruisdael, and Frans Hals. Some notable artistic styles and trends include Haarlem Mannerism, Utrecht Caravaggism, the School of Delft, the Leiden fijnschilders, and Dutch classicism. 1672 is called a disaster year" when the Dutch Republic was attacked by England, France, Münster, and Bavaria. The invading armies quickly defeated most of the Dutch States Army and conquered part of the Republic.